@metacoin, I’ve installed 15.1.1 *twice on Win 10 with a similar error. After downloading and installing, FLO autolaunches w/o a problem–no error. But when I close FLO and start the program manually, I get the error “Windows cannot access the specified device, path, or file. You may not have the appropriate permissions to access the item”. I even tried running FLO as “administrator”…same error.